CA 074 Another breakthrough towards the understanding of the

2019-07-24

Another breakthrough towards the understanding of the mechanisms responsible for stress-induced relapse to drug seeking behaviour is the evidence published by the group of Wise [34] in which they show that the activation of VTA CRF2 and not CRF1 receptors is responsible for stress-mediated relapse to cocaine seeking.

Methods for assessing TLS While the

2019-07-23

Methods for assessing TLS While the precise quantification of restricted DNA synthesis events is possible (e.g. unscheduled DNA synthesis (UDS) reveals NER), so far, it is impossible to identify TLS stretches of only a few nucleotides within the background of bulk DNA replication of normal DNA.

HA activates its receptor channels to cause an

2019-07-22

HA activates its receptor channels to cause an inward chloride flux in the insect nervous system (Hardie, 1989).

Several studies have described the role of NP in

2019-07-19

Several studies have described the role of NP in vRNP nuclear export. For example, leptomycin B (LMB), an inhibitor of the CRM1 nuclear export signal (NES) binding domain (Kudo et al., 1999), inhibits nuclear export of vRNP and NP, but not NEP or M1, in virally infected or transfected Q-VD-OPh hydrate (Elton et al., 2001, Watanabe et al., 2001).

Ultrasound is an acoustic wave with a frequency kHz

2019-07-18

Ultrasound is an acoustic wave with a frequency >20 kHz that needs a medium to propagate [20].

It was demonstrated that the addition of

2019-07-17

It was demonstrated that the addition of 10-fold excess of α-synuclein without modifications (with respect to the molar concentration of tetrameric GAPDH) leads to partial inactivation of GAPDH after 1-h incubation by 20% (Fig. 4, curve 2) in PA-824 to insignificant decrease of the specific activity of free GAPDH (Fig. 4, curve 1), which was likely due to the oxidation of the essential cysteine residues of the enzyme.

PA-824 All components of the UPP were predicted to be

2019-07-16

All components of the UPP were predicted to be susceptible to oxidative stress due to the cysteine residues in their active sites [36].

The nucleus accumbens is a critical

2019-07-15

The nucleus accumbens is a critical locus for ER/mGluR signaling in the context of addiction ER/mGluR signaling is regulated by caveolin proteins and palmitoylation

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2018-07-29